N.L. Pollesch, PhD

Nate Pollesch, PhD

Researching, developing, and applying mathematics to protect our planet and its endlessly fascinating set of inhabitants


Modeling Effects of Toxic Exposure on Wildlife Populations

Wildlife populations face a variety of natural and human-induced stressors. Ecological risk assessors frequently operate in a data limited environment. This research focuses on computational and theoretical development of modeling approaches to leverage available toxicity studies to infer population level effects of exposure on wildlife.

Network Analyses for Adverse Outcome Pathways

Adverse outcome pathways are an internationally supported and recognized methodology for organizing toxicological knowledge (www.aopwiki.org). My research in this area has focused on developing techniques to analyze information stored in AOP networks as well as approaches for using AOP knowledge to build quantitative models (qAOP).

Aggregation Theory for Multi-Criteria Assessment

We are constantly confronted with complex, high-dimensional, and diverse data sets, where the goal is to synthesize the information to give an assessment of the state of the system being measured. Assessment is ubiquitous and necessary when one wants to measure progress or changes in a system. This research considers the effect of the aggregation and normalization steps often used in multi-criteria assessment.


Stoichiometric Ecotoxicology for a Multisubstance World – BioScience (Feb 2021) [link]

Pop‐GUIDE: Population modeling Guidance, Use, Interpretation, and Development for Ecological Risk Assessment – IEAM (Dec 2020) [link]

Predicting the Probability that a Chemical Causes Steatosis Using Adverse Outcome Pathway Bayesian Networks (AOPBNs) – Risk Analysis (Nov 2019) [link]

Building and Applying Quantitative Adverse Outcome Pathway Models for Chemical Hazard and Risk Assessment – ET&C (May 2019) [link]

Extracting and Benchmarking Emerging Adverse Outcome Pathway Knowledge – ToxSci (Feb 2019) [link]

A Framework for Linking Population Model Development with Ecological Risk Assessment Objectives – IEAM (May 2018) [link] **IEAM 2018 Paper of the year**

Adverse outcome pathway networks I: Development and applications – ET&C (Feb 2018) [link]

Adverse outcome pathway networks II: Network analytics – ET&C (Feb 2018) [link]

Normalization in Sustainability Assessment – Ecol Econ (Aug 2016) [link]

Applications of Aggregation Theory to Sustainability Assessment – Ecol Econ (Apr 2015) [link]

Advocacy and Outreach

I want to live in a more curious, informed, and meaningfully connected society. I have dedicated myself to advocacy and creative communication of science and mathematics in my community.

There is no better way to advocate for science than to build connections between scientists and the communities they serve. In 2016, I founded Cafe Scientifique Twin Ports to provide a platform for local scientists to share their research, passion, and stories with the public. We have hosted discussions on everything from the Sharing Science Through Art to The Future of Humans in Space. Through Cafe Sci Twin Ports I am constantly reminded that the people in my community (and in general) are nothing short of amazing.

As rich as the Twin Ports are with talented early-career researchers, they (we) are pretty scattered among different institutions. Sensing a need, I helped start the Twin Ports Early-Career Researchers in 2016. TPER events provide a venue for early-career researchers to meet each other, share their expertise in their new community, and build skills through various workshops, panels, and discussions.

A collection of images and visualizations I’ve created are here: VIZ


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